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| Product Category: | Knockdown Validated Polyclonal Antibody |
| Synonyms: | Mitochondrial Ribosomal Protein L11; Mitochondrial Large Ribosomal Subunit Protein UL11m; 39S Ribosomal Protein L11, Mitochondrial; MRP-L11; CGI-113; L11MT; L11mt |
| UniProt Entry: | Q9Y3B7 |
| NCBI Gene Entry: | 65003 |
| Molecular Weight: | 21 kDa |
| Clonality: | Rabbit polyclonal antibody |
| Species Reactivity: | Human |
| Applications: | WB/IC |
| Recommended Dilution: | WB 1:1000/ IC 1:100 |
| Immunogen: | Recombinant fragment of human MRPL11 |
| Isotype: | Rabbit IgG |
| Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
| Storage: | At –20°C |
| Background: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. |
| Documents: | Please contact us to request the manual |
